Microfilariae Trigger Eosinophil Extracellular DNA Traps in a Dectin-1-Dependent Manner
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منابع مشابه
Extracellular DNA traps promote thrombosis.
Neutrophil extracellular traps (NETs) are part of the innate immune response to infections. NETs are a meshwork of DNA fibers comprising histones and antimicrobial proteins. Microbes are immobilized in NETs and encounter a locally high and lethal concentration of effector proteins. Recent studies show that NETs are formed inside the vasculature in infections and noninfectious diseases. Here we ...
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متن کاملHighlight : Eosinophil extra - cellular traps in Allergy
Eosinophil degranulation has always aroused the interests of physicians and scientists alike. Loss of viability and release of membrane-free granules upon eosinophil degranulation was first demonstrated by Gleich and coworkers in 1996. These free eosinophil granules, once considered as crush artifacts, are now confirmed products of eosinophil cytolysis, and suggested to be significantly pathoge...
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ژورنال
عنوان ژورنال: Cell Reports
سال: 2021
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2020.108621